10-15% of primary bone tumours
50-60 years
Male:female = 1.5:1
Most are well-differentiated low-grade tumors

Dedifferentiated chondrosarcoma:
11% undergo high grade noncartilaginous sarcoma, known as dedifferentiation - median survival 5 to 18 months; 5-year survival rate 10.5% and 13%. Most transform into osteosarcoma, second most common is fibrosarcoma

Littrell LA et al. Radiographic, CT, and MR Imaging Features of Dedifferentiated Chondrosarcomas: A Retrospective Review of 174 De Novo Cases. RadioGraphics 2004;24:1397-1409

Case reports:
1. Charles E. Lohr, Bahair H. Ghazi, Mark H. Schwab, William A. Krantz and Michelle A. Nuss. RCOM Radiological Case of the Month: Dedifferentiated chondrosarcoma. Applied Radiology. vol 36. Issue 4. Pages 42-44