Spindle cell lipoma Enzinger & Harvey (1975); Pleomorphic lipoma Shmookler & Enzinger (1981)
45 - 65 years with very common in men (90%)
Affects subcutaneous tissues of posterior neck, shoulder, back; also oral cavity, larynx, bronchus, breast, orbit, extremity. Deep ones are rare.
Commonly solitary, multiple are usually familial
Imaging shows fat and non-lipid component, which may enhance, hence difficult to differentiate from well differenitated liposarcoma
Surgical resected. Rarely recur, but no malignant potential
References:
Murphey MD et al. Benign Musculoskeletal Lipomatous Lesions. RadioGraphics 2004;24:1433-1466
